| Autor: |
Barabanova VV; St. Petersburg I. P. Pavlov State Medical University, 197022, St. Petersburg, Leo Tolstoy St., 6/8, Russia., Mikhaĭlova IA, Chefu SG, Petrishchev NN |
| Jazyk: |
ruština |
| Zdroj: |
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova [Ross Fiziol Zh Im I M Sechenova] 2001 May; Vol. 87 (5), pp. 659-64. |
| Abstrakt: |
Irradiation of the rat portal vein's fragments with the He-Ne laser for 3, 5 and 10 minutes reduced the fragments tone by half. Frequency of phasic and tonic contractions did not change, their amplitude, however, increased by neatly 40% as compared with the initial level. The NO synthase blocker N-nitro-L-arginine administered prior to the irradiation had no effect on the above parameters. The data obtained suggest that the decrease of the vessel tone is due to production of the EDRF and cGMP. The increase in the amplitude of phasic and tonic contractions of the vein's smooth muscle cells is associated with an increased Ca++ entry in each contraction cycle. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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