[Immunological status of patients with epidemic parotitis].

Autor: Agafonov AP, Strel'tsova MA, Susloparov IM, Ignat'ev GM
Jazyk: ruština
Zdroj: Voprosy virusologii [Vopr Virusol] 2001 May-Jun; Vol. 46 (3), pp. 30-3.
Abstrakt: Immunosuppression was detected in six patients with parotitis. The proliferation of peripheral blood mononuclear cells, NK activity, and CD4/CD8 index decreased, while the production of tumor necrosis factor alpha and interleukin 1 beta increased on day 1 after clinical manifestation of mumps. The clinical diagnosis of mumps was confirmed by serological analysis of paired sera. Besides parotitis virus, herpes simplex type 1 virus was detected in two saliva samples by the polymerase chain reaction. Herpes (lip vesicles) manifested in these patients on days 8 and 11 after manifestation of parotitis.
Databáze: MEDLINE