Acute hemolysis and severe neonatal hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient heterozygotes.

Autor: Kaplan M; Department of Neonatology, Shaare Zedek Medical Center, and the Faculty of Medicine of the Hebrew University, Jerusalem, Israel., Hammerman C, Vreman HJ, Stevenson DK, Beutler E
Jazyk: angličtina
Zdroj: The Journal of pediatrics [J Pediatr] 2001 Jul; Vol. 139 (1), pp. 137-40.
DOI: 10.1067/mpd.2001.115312
Abstrakt: Two premature female infants had severe hyperbilirubinemia caused by hemolysis. Both neonates were heterozygotes for the glucose-6-phosphate dehydrogenase Mediterranean mutation as determined by DNA analysis. Glucose-6-phosphate dehydrogenase-deficient heterozygotes may be susceptible to the complications of this enzyme deficiency.
Databáze: MEDLINE