| Autor: |
Cummings TJ; Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA., Ebert RH 2nd, Provenzale J, McLendon RE |
| Jazyk: |
angličtina |
| Zdroj: |
Brain pathology (Zurich, Switzerland) [Brain Pathol] 2001 Jul; Vol. 11 (3), pp. 391-3. |
| Abstrakt: |
The March COM: A 16 year old female presented with headaches and cerebellar dysfunction. MR images showed a mass lesion of the right cerebellar hemisphere with mass effect on the medulla. The mass exhibited a striated pattern of alternating isointense and hypointense zones on T1-weighted images that did not contrast enhance. The lesion was hyperintense on T2-weighted images, and also showed a striated appearance. A suboccipital craniotomy and resection of the lesion was performed. Microscopically, the specimen consisted of widened folia and a disorganized cerebellar architectonic pattern in which the internal granular cell layer was occupied by a population of large dysmorphic nerve cell bodies. Patient's diagnosed with Lhermitte-Duclos disease must be adequately evaluated for Cowden's syndrome. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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