| Autor: |
Lewis CM; National Human Genome Research Institute, National Institutes of Health, 20892, Bethesda, MD, USA., Broussard C, Czar MJ, Schwartzberg PL |
| Jazyk: |
angličtina |
| Zdroj: |
Current opinion in immunology [Curr Opin Immunol] 2001 Jun; Vol. 13 (3), pp. 317-25. |
| DOI: |
10.1016/s0952-7915(00)00221-1 |
| Abstrakt: |
The Tec kinases are implicated as important components of the antigen receptor signaling required for proper lymphocyte activation and development. Recent data suggest that these kinases contribute to multiprotein complexes containing LAT and SLP-76 in T cells, and BLNK/SLP-65 in B cells, which are required for activation of PLC-gamma and downstream pathways. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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