| Autor: |
Bavis RW; Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA. bavisr@svm.vetmed.wisc.edu, Kilgore DL Jr |
| Jazyk: |
angličtina |
| Zdroj: |
Respiration physiology [Respir Physiol] 2001 Jul; Vol. 126 (3), pp. 183-99. |
| DOI: |
10.1016/s0034-5687(01)00206-7 |
| Abstrakt: |
To test the hypothesis that the adult ventilatory response to CO2 can be modified by exposure to CO2 during development, we exposed Japanese quail (Coturnix japonica) from two populations to 2% CO2 throughout embryonic development. The ventilatory response to 6% CO2 was subsequently measured in control and CO2-exposed quail following a 6-9 week deacclimation period. In one population of quail, CO2-exposed female, but not male, quail had a reduced ventilatory response to 6% CO2 as adults (P<0.001). Although control and CO2-exposed quail had similar ventilation while breathing air, CO2-exposed females exhibited a 26% reduction in mean ventilation at 6% CO2, primarily due to a reduced tidal volume. In contrast, the identical incubation treatment had no effect on the ventilation of either gender in a second population of quail. It appears that developmental plasticity in the hypercapnic ventilatory response may generally be greater in females, although this conclusion may vary depending on genetic factors. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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