Alcohol actions on GABA(A) receptors: from protein structure to mouse behavior.

Autor: Ueno S; Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas 78712, USA., Harris RA, Messing RO, Sanchez-Perez AM, Hodge CW, McMahon T, Wang D, Mehmert KK, Kelley SP, Haywood A, Olive MF, Buck KJ, Hood HM, Blednov Y, Findlay G, Mascia MP
Jazyk: angličtina
Zdroj: Alcoholism, clinical and experimental research [Alcohol Clin Exp Res] 2001 May; Vol. 25 (5 Suppl ISBRA), pp. 76S-81S.
DOI: 10.1097/00000374-200105051-00014
Abstrakt: This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were R. Adron Harris and Susumu Ueno. The presentations were (1) Protein kinase Cepsilon-regulated sensitivity of gamma-aminobutyric acid type A (GABAA) receptors to allosteric agonists, by Robert O. Messing, A. M. Sanchez-Perez, C. W. Hodge, T. McMahon, D. Wang, K. K. Mehmert, S. P. Kelley, A. Haywood, and M. F. Olive; (2) Genetic and functional analysis of a GABAA receptor gamma2 subunit variant: A candidate for quantitative trait loci involved in alcohol sensitivity and withdrawal, by Kari J. Buck and Heather M. Hood; (3) Tryptophan-scanning mutagenesis in GABAA receptor subunits: Channel gating and alcohol actions, by Susumu Ueno; and (4) Can a single binding site account for actions of alcohols on GABAA and glycine receptors? by R. Adron Harris, Yuri Blednov, Geoffrey Findlay, and Maria Paola Mascia.
Databáze: MEDLINE