| Autor: |
Alonso GD; Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigaciones Científicas y Técnicas, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina., Pereira CA, Remedi MS, Paveto MC, Cochella L, Ivaldi MS, Gerez de Burgos NM, Torres HN, Flawiá MM |
| Jazyk: |
angličtina |
| Zdroj: |
FEBS letters [FEBS Lett] 2001 Jun 01; Vol. 498 (1), pp. 22-5. |
| DOI: |
10.1016/s0014-5793(01)02473-5 |
| Abstrakt: |
In epimastigotes of Trypanosoma cruzi, the etiological agent of Chagas' disease, arginine kinase activity increased continuously during the exponential phase of growth. A correlation between growth rate, enzyme-specific activity and enzyme protein was observed. Arginine kinase-specific activity, expressed as a function of enzyme protein, remains roughly constant up to 18 days of culture. In the whole range of the culture time mRNA levels showed minor changes indicating that the enzyme activity is post-transcriptionally regulated. Arginine kinase could be proposed as a modulator of energetic reserves under starvation stress condition. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
Plný text