Paramecium genome survey: a pilot project.

Autor: Dessen P; Service de Bioinformatique, UMS825 CNRS/SC13 INSERM, 7 rue Guy Môquet BP8, 94801 Villejuif Cedex, France., Zagulski M, Gromadka R, Plattner H, Kissmehl R, Meyer E, Bétermier M, Schultz JE, Linder JU, Pearlman RE, Kung C, Forney J, Satir BH, Van Houten JL, Keller AM, Froissard M, Sperling L, Cohen J
Jazyk: angličtina
Zdroj: Trends in genetics : TIG [Trends Genet] 2001 Jun; Vol. 17 (6), pp. 306-8.
DOI: 10.1016/s0168-9525(01)02307-1
Abstrakt: A consortium of laboratories undertook a pilot sequencing project to gain insight into the genome of Paramecium. Plasmid-end sequencing of DNA fragments from the somatic nucleus together with similarity searches identified 722 potential protein-coding genes. High gene density and uniform small intron size make random sequencing of somatic chromosomes a cost-effective strategy for gene discovery in this organism.
Databáze: MEDLINE