Naphthopyranone glycosides from Paepalanthus microphyllus.

6)-beta-D-glucopyranoside (1), paepalantine-9-O-alpha-L-arabinopyranosyl-(1-->6)-beta-D-glucopyranoside (2), and paepalantine-9-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (3), along with the known paepalantine-9-O-beta-D-glucopyranoside (4) were isolated from aerial parts of Paepalanthus microphyllus. These compounds were characterized by spectrometric methods, including electrospray mass spectrometry and 1D and 2D NMR experiments. As a part of our program for screening natural compounds for anti-HIV activity, compounds 1-4 were tested in C8166 cells infected with HIV-1MN. -->
Substance Nomenclature: 0 (Anti-HIV Agents)
0 (Glycosides)
Entry Date(s): Date Created: 20010526 Date Completed: 20010906 Latest Revision: 20190906
Update Code: 20240829
DOI: 10.1021/np000518g
PMID: 11374977
Autor: Piacente S; Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Via Ponte Don Melillo 84084, Fisciano, SA, Italy., Campaner Dos Santos L, Mahmood N, Zampelli A, Pizza C, Vilegas W
Jazyk: angličtina
Zdroj: Journal of natural products [J Nat Prod] 2001 May; Vol. 64 (5), pp. 680-2.
DOI: 10.1021/np000518g
Abstrakt: Three new naphthopyranone glycosides, paepalantine-9-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside (1), paepalantine-9-O-alpha-L-arabinopyranosyl-(1-->6)-beta-D-glucopyranoside (2), and paepalantine-9-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (3), along with the known paepalantine-9-O-beta-D-glucopyranoside (4) were isolated from aerial parts of Paepalanthus microphyllus. These compounds were characterized by spectrometric methods, including electrospray mass spectrometry and 1D and 2D NMR experiments. As a part of our program for screening natural compounds for anti-HIV activity, compounds 1-4 were tested in C8166 cells infected with HIV-1MN.
Databáze: MEDLINE
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