| Autor: |
Coscia JM; Department of Psychology, Vanderbilt University, Nashville, Tennessee 37203, USA., Christensen BK, Henry RR |
| Jazyk: |
angličtina |
| Zdroj: |
Pediatric AIDS and HIV infection [Pediatr AIDS HIV Infect] 1997 Apr; Vol. 8 (2), pp. 108-13. |
| Abstrakt: |
Although biologic and environmental risk factors show an age-dependent effect on children's cognitive development, outcome studies have yet to consider the role such factors play in the development of children born to HIV-1-infected women. This study explored the age-dependent differential impact of such risk factors on the cognitive functioning of children exposed in utero to HIV-1. Eighty-two children were administered a standardized measure of cognitive functioning and divided into two groups depending on their age when tested. Group 1 included children age 2 to 29 months (n = 46); Group 2 included children age 30 to 101 months (n = 36). Correlations between cognitive test scores and specific risk factors revealed an age-related double-dissociation. Serostatus and percent of CD4 cells correlated moderately with cognitive test scores in Group 1; however, these correlations were attenuated and nonsignificant in Group 2. Conversely, caregiver status and cognitive test scores were uncorrelated in Group 1, but were correlated in Group 2. These findings support a risk and resilience model of development. That is, in the context of biologic risk factors, aspects of the child's environment may either facilitate or hinder cognitive development. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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