Determinants of genital human papillomavirus detection in a US population.

Autor: Peyton CL; University of New Mexico, Department of Molecular Genetics and Microbiology, Albuquerque, New Mexico 87131-5276, USA., Gravitt PE, Hunt WC, Hundley RS, Zhao M, Apple RJ, Wheeler CM
Jazyk: angličtina
Zdroj: The Journal of infectious diseases [J Infect Dis] 2001 Jun 01; Vol. 183 (11), pp. 1554-64. Date of Electronic Publication: 2001 May 09.
DOI: 10.1086/320696
Abstrakt: This study investigated the association of selected demographic and behavioral characteristics with the detection of low-risk, high-risk, and uncharacterized genital human papillomavirus (HPV) in women attending clinic for routine nonreferral gynecologic health care. Cervical specimens obtained from 3863 women 18-40 years old (mean, 28 years) with no history of high-grade cervical disease were analyzed for 38 HPV types. Overall, HPV prevalence was 39.2%. The prevalence of high-risk, low-risk, and uncharacterized HPV types was 26.7%, 14.7%, and 13.0%, respectively. As expected, the characteristics most strongly associated with overall HPV detection were age and numbers of lifetime and recent sex partners. Low-risk, high-risk, and uncharacterized HPV detection increased with increasing numbers of sex partners. There was a decline in high-risk and low-risk HPV detection with increasing age but little change in uncharacterized HPV detection. These results suggest that the uncharacterized HPV types have a different natural history than either low-risk or high-risk HPV types.
Databáze: MEDLINE