Celiac vagotomy reduces suppression of feeding by jejunal fatty acid infusions.

Autor: Cox JE; Department of Psychology, Campbell Hall, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Tyler WJ, Randich A, Kelm GR, Meller ST
Jazyk: angličtina
Zdroj: Neuroreport [Neuroreport] 2001 May 08; Vol. 12 (6), pp. 1093-6.
DOI: 10.1097/00001756-200105080-00009
Abstrakt: We investigated the role of the celiac branch of the vagus nerve in suppression of food intake produced by jejunal fatty acids infusions. Following selective celiac vagotomy or sham surgery, adult, male Sprague-Dawley rats received 7 h infusions of linoleic acid or saline through indwelling jejunal catheters on four consecutive days. Although linoleic acid still produced significant suppression of intake in rats with celiac vagotomy, it was less effective in these animals than in controls. The temporal pattern of results suggested that celiac afferent fibers are involved in mediating both pre- and postabsorptive effects of infused fatty acids.
Databáze: MEDLINE