Autor: |
Gusev GP, Lozhkina TK, Matiukhina LT, Saltykova IA, Sololova MM |
Jazyk: |
ruština |
Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1975 Mar; Vol. 79 (3), pp. 63-5. |
Abstrakt: |
Experiments were conducted on rats. A study was made of water, sodium, potassium and creatine excretion 3 hours after the administration into the stomach of a 5% load with a 0.9% NaCl solution. In comparison with control, sodium excretion decreased considerably in the animals given 2 mg per 100 g of weight of trioxylupane or heterobetulin; water, potassium and creatine excretion remained unchanged. Sodium and water excretion increased with administration of dioxylupenal in a dose of 2 mg per 100 g of weight. Heterobetulin also increased the urinary potassium excretion under conditions of administration to rats of a 5% load with a 1.25% KCl solution. The data obtained were of interest for the understanding of the interrelationship between the structure of the substances and their physiological activity. |
Databáze: |
MEDLINE |
Externí odkaz: |
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