| Autor: |
Padmanabhan S; Cambridge NeuroScience, Inc., Norwood, MA 02602, USA. padman@cambneuro.com, Perlman ME, Zhang L, Moore D, Zhou D, Fischer JB, Durant GJ, McBurney RN |
| Jazyk: |
angličtina |
| Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2001 Feb 26; Vol. 11 (4), pp. 501-4. |
| DOI: |
10.1016/s0960-894x(00)00695-8 |
| Abstrakt: |
The identification and characterization of a potentially ischemia-selective and orally-active sulfoxide based NMDA ion-channel blocker showing good neuroprotective activity, (R)-(+)-N-(2-chloro-5-methylthiophenyl)-N'-(3-methylsulfinylphenyl)-N'-methylguanidine (CNS 5788), is described. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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