| Autor: |
Beijer C; Klinisch-Chemisch Laboratorium, Diaconessenhuis, Postbus 9650, 2300 RD Leiden., Planken EV |
| Jazyk: |
Dutch; Flemish |
| Zdroj: |
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2001 Jan 13; Vol. 145 (2), pp. 90-3. |
| Abstrakt: |
An 86-year-old woman presented with anorexia, thirst and nycturia. Laboratory results revealed a hypercalcaemia with renal failure. The patient used 1-6 vitamin A-D tablets daily (1 tablet contains 600 IU retinol palmitate and 200 IU cholecalciferol). The diagnosis was: hypercalcaemia due to chronic vitamin A ingestion. This diagnosis was supported by the finding of the elevated vitamin A concentration in the patient's serum and the exclusion of other causes of hypercalcaemia. In chronic vitamin A ingestion risk factors for vitamin A toxicity are age, body weight and renal insufficiency. The hypercalcaemia caused by chronic vitamin A ingestion is explained through the up-regulation of osteoclasts by retinol metabolites. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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