Neurological manifestations of children with systemic lupus erythematosus.

Autor: Loh WF; Paediatric Institute, Hospital Kuala Lumpur, Jalan Pahang, 50586 Kuala Lumpur., Hussain IM, Soffiah A, Lim YN
Jazyk: angličtina
Zdroj: The Medical journal of Malaysia [Med J Malaysia] 2000 Dec; Vol. 55 (4), pp. 459-63.
Abstrakt: In a cross-sectional study of 21 children with Systemic Lupus Erythematosus, 15 (71%) were found to have neuropsychiatric manifestations. The most common finding was generalised seizures (42.8%) followed by encephalopathy (19%) and hallucinations (19%). One child (4.76%) had hemichorea. In 3 children neurological manifestations were the first symptom of SLE. Computerised Axial Tomograms (CAT scans) showed cerebral atrophy in 7 of 12 scans available for review. Ten children had abnormal EEGs. Although none of the children had clinical evidence of a peripheral neuropathy, 8 had neurophysiological evidence of a neuropathy. One child died of intracranial haemorrhage. Six children had residual neuropsychiatric sequalae.
Databáze: MEDLINE