Tru-cut biopsy of palpable breast lesions: a practical option for pre-operative diagnosis in developing countries.
| Autor: | Gukas ID; Department of Surgery, Jos University Teaching Hospital, Nigeria., Nwana EJ, Ihezue CH, Momoh JT, Obekpa PO |
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| Jazyk: | angličtina |
| Zdroj: | The Central African journal of medicine [Cent Afr J Med] 2000 May; Vol. 46 (5), pp. 127-30. |
| DOI: | 10.4314/cajm.v46i5.8536 |
| Abstrakt: | Objectives: To establish the role of Tru-cut needle biopsy in the pre-operative diagnosis of breast lesions in a developing country. Design: Prospective cross sectional study. Subjects: 112 consecutive patients with palpable breast lesions who had both Tru-cut and excision biopsy as a pre-operative diagnostic procedure. Results: Four (3.6%) patients had specimens that were inadequate for histological diagnosis. Tru-cut biopsy diagnosed 42 of the remaining 108 as malignant and 66 as benign, but only 40 and 61 respectively were confirmed to be correctly so by excision biopsy. Tru-cut biopsy, therefore, achieved a sensitivity of 88.9% (95% CI 79.7 to 98.1) specificity of 96.8% (95% CI 92.5 to 100) and an over all diagnostic accuracy of 93.5% (95% CI 88.9 to 98.2). There was a false positive rate of 4.8%, a false negative rate of 7.6% and a positive predictive value of 95.2%. The pathologist was able to make a correct specific histological diagnosis in 76.2% of all the adequate Tru-cut samples. Conclusion: If Tru-cut biopsy is done instead of excision biopsy, it will sufficiently reduce waiting time and reduce cost (four fold). It is well tolerated by patients. We regard the procedure as a useful adjunct and indeed a practical option for accurate pre-operative diagnosis of palpable breast lesions. |
| Databáze: | MEDLINE |
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