Antiallergic activity of 4-hydroxy-3-nitrocoumarins.

Autor: Buckle DR, Cantello BC, Smith H, Spicer BA
Jazyk: angličtina
Zdroj: Journal of medicinal chemistry [J Med Chem] 1975 Apr; Vol. 18 (4), pp. 391-4.
DOI: 10.1021/jm00238a014
Abstrakt: Twenty-four substituted 4-hydroxy-3-nitrocoumarins have been prepared for nitration of the corresponding 4-hydroxycoumarins. All were found to possess antiallergic activity as measured by the homocytotropic antibody-antigen induced passive cutaneous anaphylaxis reaction in the rat.
Databáze: MEDLINE