[Metabolism of catecholamines in children with attention deficit syndrome with hyperactivity].
| Autor: | Kasatikova EV, Larionov NP, Popkova EV, Briazgunov IP |
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| Jazyk: | ruština |
| Zdroj: | Voprosy meditsinskoi khimii [Vopr Med Khim] 2000 Sep-Oct; Vol. 46 (5), pp. 455-61. |
| Abstrakt: | Unlabelled: The aim of research was to study catecholamine excretion peculiarities of the children with attention deficit hyperactivity disorder (ADHD). 25 children at the age of 7-9 years took part in this research. High-pressure liquid chromatography (HPLC) was used for measuring the content of catecholamine. The content of catecholamine was defined in the morning samples of urine. The examination showed, that ADHD children had the basal level of epinephrine and norepinephrine more than the normal control in 3.9 and 5.4 times. After cognitive tests the content of norepinephrine reduced in the ADHD group in 2.1 times in the comparison with normal control. On the contrary content of epinephrine increased in 2.8 times. Conclusion: Simpatico-adrenal system hyperactivity (especially it's adrenals component) characterized ADHD children. |
| Databáze: | MEDLINE |
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