| Autor: |
Wooten MD; Sections of Rheumatology and Cardiology, Department of Veterans Affairs Regional Medical Center, Wilmington, Delaware,USA., Reddy GV, Johnson RD |
| Jazyk: |
angličtina |
| Zdroj: |
Delaware medical journal [Del Med J] 2000 Dec; Vol. 72 (12), pp. 517-9. |
| Abstrakt: |
A 57-year-old man with nodular rheumatoid arthritis was started on a combination of etanercept and methotrexate. After treatment for five months on this therapy, he presented with new-onset atrial fibrillation. While this report is anecdotal, any new drug warrants intense monitoring for unexpected toxicities in the post-marketing period. Etanercept is being tried in patients with congestive heart failure, where TNF-a seems to be increased. Further surveillance and caution are suggested in patients with known coronary artery disease or atrial dysrhythmia. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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