[Nocturnal drop of arterial blood pressure: determinant factors and relationship with organic damage secondary to hypertension].
| Autor: | Cabrera Vélez R; Unidad de Investigación del Area 5 de Madrid (Atención Primaria y Hospital La Paz), Madrid., Martínez López MA, Torre Carballada A, Aguirre de Cárcer Escolano A, Seguido Aliaga P, Sáenz del Castillo I, Polo Gómez E, Alcaide Martín MJ, García Puig J |
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| Jazyk: | Spanish; Castilian |
| Zdroj: | Atencion primaria [Aten Primaria] 2000 Nov 30; Vol. 26 (9), pp. 607-13. |
| DOI: | 10.1016/s0212-6567(00)78732-4 |
| Abstrakt: | Objectives: To evaluate the night-time drop in blood pressure in patients with light hypertension and to determine its possible relationship with damage in key organs. Design: Cross-sectional study. Setting: Eight urban health centres. Patients: Four hundred and eighteen adults with light-moderate hypertension. Interventions: a) Blood pressure reading on three visits; b) ambulatory monitoring of pressure for 24 hours; c) echocardiograph (in 219 patients); d) albuminuria determination (in 134 patients). A night-time drop in blood pressure was defined as the difference between day and night ambulatory pressures; and relative drop, as the night-time pressure drop as a percentage of the day-time pressure. Results: Night-time drop in systolic and diastolic pressures was 13.6 (10.7) and 12.1 (8.6) mmHg, respectively. The predictive factors of night-time drop in blood pressure were, directly, daily ambulatory blood pressure (p < 0.05) and female gender (p < 0.05) and, inversely, age (p < 0.05). No association was observed between night-time drop in blood pressure and left ventricular mass. Only in women was an independent relationship found, inversely, between night-time drop in blood pressure and urinary excretion of albumin (p < 0.05). Conclusions: Relative night-time drop in blood pressure is greater in women than in men, diminishes with age and depends on the day-time ambulatory pressure. In women a minor night-time drop in blood pressure is associated with greater organic damage. |
| Databáze: | MEDLINE |
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