The utilisation of nuchal translucency as a prenatal marker of Down syndrome, 1993-1999.

Autor: Mulvey SF; Department of Obstetrics and Gynaecology, Monash University Clayton, Victoria, Australia., Atchison WG, Grimwade JC, Renou PM, Shekleton PA, Wallace EM
Jazyk: angličtina
Zdroj: The Australian & New Zealand journal of obstetrics & gynaecology [Aust N Z J Obstet Gynaecol] 2000 Nov; Vol. 40 (4), pp. 423-6.
DOI: 10.1111/j.1479-828x.2000.tb01173.x
Abstrakt: A sample of 6,038 obstetric ultrasound referrals and reports between January 1993 and June 1999 in a single Melbourne private ultrasound practice was reviewed to determine whether the referral and reporting pattern for nuchal translucency (NT) measurement has changed. The proportion of both 10-14 week ultrasound scans and mid trimester fetal anatomy scan referrals increased significantly over the study period (p < 0.001 and p < 0.001, respectively). There was also a significant increase in NT reporting and the number of specific referrals for an NT measurement over the study period (p = 0.01 and p < 0.001, respectively). If current trends continue it is likely that the 10-14 week scan for NT measurement will become a routine component of antenatal care. Therefore, as a matter of urgency, it is imperative that the best and most cost-effective screening strategy for Down syndrome in an Australian population is defined.
Databáze: MEDLINE