| Autor: |
Scelsa SN; Department of Neurology, Beth Israel Medical Center, New York, New York, USA. SScelsa@BethIsraelNY.Org, Herskovitz S |
| Jazyk: |
angličtina |
| Zdroj: |
Electromyography and clinical neurophysiology [Electromyogr Clin Neurophysiol] 2000 Dec; Vol. 40 (8), pp. 497-502. |
| Abstrakt: |
Controversy exists concerning whether Miller Fisher syndrome (MFS) is the result of a predominantly axonal or demyelinating polyneuropathy and whether the Guillain-Barré syndrome variant of acute ataxia and areflexia without ophthalmoplegia, ataxic Guillain-Barré syndrome (atxGBS), has a distinct pathophysiology. We explored these issues by reviewing the electrophysiologic features of 6 patients with MFS and 2 patients with atxGBS. EMG laboratory records were reviewed and electrophysiologic findings were categorized as axonal or demyelinating neuropathy using previously defined criteria. Of the 6 patients with MFS, 5 had electrophysiologic evidence suggestive of an axonal, predominantly sensory polyneuropathy; only 1 patient met criteria for demyelinating polyneuropathy. Both patients with atxGBS had demyelinating sensorimotor polyneuropathy. Electrophysiologic abnormalities in MFS typically suggest a predominantly axonal, sensory polyneuropathy, though demyelinating forms occur and may be under-diagnosed using current criteria. AtxGBS, in our experience, is a predominantly demyelinating polyneuropathy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
