| Autor: |
Vincent T; Division of Pulmonary and Critical Care Medicine, New York, New York, and the Karolinska Institute, Stockholm, Sweden., Harvey BG, Hogan SM, Bailey CJ, Crystal RG, Leopold PL |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of virology [J Virol] 2001 Feb; Vol. 75 (3), pp. 1516-21. |
| DOI: |
10.1128/JVI.75.3.1516-1521.2001 |
| Abstrakt: |
Neutralizing antiviral antibodies are typically detected on the basis of inhibition of viral function, such as propagation of a viral infection or inhibition of viral gene expression. Evidence is presented that anti-adenovirus neutralizing antibodies can be evaluated by analysis of cell-associated capsids or by analysis of intracellular trafficking of the capsids within 1 h after infection. Quantitative analyses of these morphologic parameters represent rapid, broadly applicable, functional assays for the detection of anti-adenovirus neutralizing antibodies. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
