| Autor: |
Horne G; Department of Reproductive Medicine, St Mary's Hospital, Manchester M13 0JH, UK. greg.smh1.cmht.nwest.nhs.uk, Atkinson A, Brison DR, Radford J, Yin JA, Edi-Osagie EC, Pease EH, Lieberman BA |
| Jazyk: |
angličtina |
| Zdroj: |
Human reproduction (Oxford, England) [Hum Reprod] 2001 Jan; Vol. 16 (1), pp. 107-109. |
| DOI: |
10.1093/humrep/16.1.107 |
| Abstrakt: |
Two cases are reported of successful pregnancies following long-term semen banking prior to chemotherapy and radiotherapy for malignancy. With the first case, the patient banked semen at the age of 20 years prior to chemotherapy for Hodgkin's disease; 11 years later the thawed semen was used for IVF with intracytoplasmic sperm injection (ICSI), resulting in twins being born following the transfer of frozen-thawed embryos. In the second case, the patient banked semen at the age of 17 years prior to chemotherapy and radiotherapy for acute myeloid leukaemia; 8 years later it was used for ICSI, resulting in triplets being born following the transfer of frozen-thawed embryos. These cases support long-term semen banking for men whose future fertility may be compromised by suppression of spermatogenesis secondary to administration of chemo/radiotherapy treatment. The advent of successful ICSI combined with embryo cryopreservation has increased the chance of thawed cryopreserved semen achieving fertilization. Banking of a single ejaculate prior to commencement of chemotherapy/radiotherapy treatment may preserve potential fertility without compromising the oncology treatment. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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