| Autor: |
Godzhaev NM; Rasulzade Baku State University, Azerbaijan., Agaeva GA |
| Jazyk: |
ruština |
| Zdroj: |
Biofizika [Biofizika] 2000 Jul-Aug; Vol. 45 (4), pp. 581-5. |
| Abstrakt: |
The spatial structures of human immunoglobulin E pentapeptide Asp-Ser-Asp-Pro-Arg and some of its related peptides were investigated by the method of theoretical conformational analysis. These synthetic peptides have the capacity to inhibit the binding of immunoglobulin E to the mast cells of the skin. The results of the calculations and the data on biological activity of these peptides were used for determination their energy-dependent conformational characteristics that provide their specific interaction with receptors of mast cells. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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