[Oncovirus-induced permanent genetic instability in Drosophila melanogaster].

Autor: Mit' NV; Department of Genetics and Molecular Biology, Al-Farabi State University Kazakhstan, Almaty., Dzhansugurova LB, Bersimbaev RI
Jazyk: ruština
Zdroj: Genetika [Genetika] 2000 Aug; Vol. 36 (8), pp. 1033-40.
Abstrakt: Mutant alleles of a system of genetic instability induced by oncoviral DNAs were shown to demonstrate an unstable manifestation 500 generations after their emergence. A cytogenetic analysis of oncovirus-induced unstable lines has revealed numerous chromosome rearrangements. For the Lobe alleles of this system, a specific chromosome rearrangement, Df(2L) = 35C-36B, was found on the left arm of chromosome 2. We used recessive lethal mutations involving DNA rearrangements in a successful construction of cross systems for "explosive" instability.
Databáze: MEDLINE