| Autor: |
Raouf H; Service d'Hématologie, Hôpital Aziza Othmana., Balkis M, Emna G, Lamia A, Rihane BL, Hela BA, Zaher BA, Aicha H |
| Jazyk: |
francouzština |
| Zdroj: |
La Tunisie medicale [Tunis Med] 2000 Mar; Vol. 78 (3), pp. 176-80. |
| Abstrakt: |
We report various pulmonary complications occurring in 88 patients with sickle cell disease: 44 Hb SS, 29 Hb Sb and 15 Hb SC. Pulmonary infections were observed in 20% of patients, and initiated the disease in 7% of cases. They were common in children younger than 10 years especially in Hb SS and Hb Sb patients. Bacteria were identified in 50% of cases predominantly S. pneumoniae, Mycoplasma pneumoniae, and Haemophilus influenzae. Acute chest syndrome occurred in adolescents and adults and was the consequence of pulmonary infarct or embolism which should be differentiated from bacterial pneumonia. Restrive syndrome was present in 2/3 of patients. It was associated to hypoxemia in 80% of cases. Prophylactic therapy was of paramount importance on long-term penicillin therapy and on closely-spaced immunization against pneumococci and Haemophilus influenzae. Blood exchange are indicated in severe hypoxemia. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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