| Autor: |
Dickler HB, Cone JL, Kubicek MT, Sachs DH |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of experimental medicine [J Exp Med] 1975 Sep 01; Vol. 142 (3), pp. 796-801. |
| DOI: |
10.1084/jem.142.3.796 |
| Abstrakt: |
Antibodies contained in an A/J anti-B10 antiserum, when tested on lymphocytes from B10.A mice, were shown to bind to both B and T cells and to inhibit the binding of Ig complexes to the Fc receptors of B lymphocytes. These antibodies could be removed by absorption with B10.D2 lymphocytes. Similar results were obtained with lymphocytes from two to six (B6A)F1 x A/J backcross mice which had H-2a/a genotype. These data indicate that alloantigens determined by at least one non-H-2 locus are associated with or a part of Fc receptors. These antigens may be similar in structure and function to Ia antigens. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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