A paradoxical idea of cancer's resolution.

Autor: Gogichadze GK; Institute of Hematology and Blood Transfusion, Tbilisi, Georgia., Gedenidze AV
Jazyk: angličtina
Zdroj: Medical hypotheses [Med Hypotheses] 2000 Oct; Vol. 55 (4), pp. 300-1.
DOI: 10.1054/mehy.2000.1055
Abstrakt: Polykaryocytes arising by means of fusion represent genetic deadlock. They cannot enter the S-phase of mitosis and they die quickly. A concept of cancer treatment proposes the conversion of tumor cells synchronously into the stage of unviable polykaryocytes, which leads to dissociation of the tumor substrate, reduction of the mass of tumor, and even to its resolution. Under echoscopic control, it is proposed to introduce into the tumor a solution ofwell-known fusogenic agents, such as polyethylene glycol (PEG) with the 15% dimethylsulfoxide (DMSO).
(Copyright 2000 Harcourt Publishers Ltd.)
Databáze: MEDLINE