| Abstrakt: |
Reactions to the geometrical configuration of the underlying surface of fibroblast-like cells of various species (mouse, rat, chick, hamster, human) were compared quantitatively. All normal cells migrated from 25-40 mcm deep grooves but not from the less deep ones -5-15 mcm. Migration ability was the highest in the mouse cells;it was less pronounced in rat and chick cells; hamster and human cells had the lowest migration ability. The offered quantitative method can be used for estimation of the reaction to the ordered relief of the substratum of different minds of cultured cells - normal as well as pathologically changed. |
