| Autor: |
Viani MB; Department of Physics, University of California at Santa Barbara, Santa Barbara, California 93106, USA. viani@physics.ucsb.edu, Pietrasanta LI, Thompson JB, Chand A, Gebeshuber IC, Kindt JH, Richter M, Hansma HG, Hansma PK |
| Jazyk: |
angličtina |
| Zdroj: |
Nature structural biology [Nat Struct Biol] 2000 Aug; Vol. 7 (8), pp. 644-7. |
| DOI: |
10.1038/77936 |
| Abstrakt: |
We have used a prototype small cantilever atomic force microscope to observe, in real time, the interactions between individual protein molecules. In particular, we have observed individual molecules of the chaperonin protein GroES binding to and then dissociating from individual GroEL proteins, which were immobilized on a mica support. This work suggests that the small cantilever atomic force microscope is a useful tool for studying protein dynamics at the single molecule level. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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