[Decreasing prevalence of Helicobacter pylori: a consequence of treatment of gastroduodenal ulcers].

Autor: van der Weerd NC; Academisch Ziekenhuis Vrije Universitet, afd. Gastro-enterologie, Amsterdam., Cats A, Thijs JC, Festen HP, Meuwissen SG, Kuipers EJ
Jazyk: Dutch; Flemish
Zdroj: Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2000 Jul 15; Vol. 144 (29), pp. 1385-8.
Abstrakt: Four patients with gastroduodenal ulcers in the absence of Helicobacter pylori illustrate the decreasing prevalence of this microorganism. One was a 19-year-old boy with nausea, diarrhoea and weight loss caused by multiple gastroduodenal ulcers due to the Zollinger-Ellison syndrome. Another was a 36-year-old man with abdominal discomfort caused by an ulcer due to Crohn's disease. The other two cases concerned a 29-year-old man and a 68-year-old woman with relapsing ulcer disease and active bleeding, in whom no causal factors could be determined. Recent studies suggest a decreasing prevalence of H. pylori leading to both a relative and an absolute decrease of gastroduodenal ulcers attributed to H. pylori. Future treatment strategies will have to take these altered prevalence rates into consideration.
Databáze: MEDLINE