| Autor: |
Aznabaev MT, Speranskiĭ VV, Aznabaev RA, Golovin VP, Iakovleva VG, Aznabaeva LF |
| Jazyk: |
ruština |
| Zdroj: |
Vestnik oftalmologii [Vestn Oftalmol] 2000 May-Jun; Vol. 116 (3), pp. 21-5. |
| Abstrakt: |
Nonspecific and specific immunity values were studied in 70 children before and in various periods after 74 operations on the anterior segment of the eyeball. In children with persistent autosensitization to ocular tissue autoantigens (alpha-crystalline and S-antigen) postoperative uveitis presented as an immunocomplex disease with signs of exhaustion of the functional potential of the phagocytosis and complement systems. In children without autosensitization uveitis was associated with immunity activation. Phagocytosis system and cooperation of lymphocyte subpopulations, including normal killers (CD16+), play an important role in prevention of sensitization to ocular tissue autoantigens. Therefore, complex immunological examinations of children before surgery and regular check-ups after it will help differentiate immunodeficiency from compensatory immunosuppression preventing autoimmune disease, which is important in prescription of immunostimulating therapy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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