| Autor: |
Buslovich SIu, Borushko NV |
| Jazyk: |
ruština |
| Zdroj: |
Farmakologiia i toksikologiia [Farmakol Toksikol] 1976 Jun-Aug; Vol. 39 (4), pp. 481-3. |
| Abstrakt: |
A 24-hour stay of the Rana temporaria tadpoles in solutions of the sodium and diethylamine salts of 2,4-dichlorophenoxyacitic acid (with 1 and 2 mg/l, respectively) significantly inhibits their metamorphosis. An addition of these salts to a solution containing thyroidin in a concentration of 1--5 mg/l hinders the action of hormone stimulating metamorphosis. The effect of the sodium salt of 2,4-dichlorophenoxyacetic acid prevents the destruction of some tadpoles by toxic concentrations of thyroidin. The above data justify referring the chloroderivatives of the phenoxyacetic acid to antagonists of the thyroid hormones. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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