[A cultured concentrated inactivated vaccine against tick-borne encephalitis studied during the immunization of children and adolescents].

Autor: Pavlova LI; Tarasevich State Research Institute for Standardization and Control of Medical Biological Preparations, Moscow, Russia., Gorbunov MA, Vorob'eva MS, Karavanov AS, Grachev VP, Ladyshenskaia IP, Rasshchepkina MN, Mel'nikova LN, Lebedeva TM, Mel'nikov NA, Gusmanova AG, Deviatkov MIu, Rozanova EV, Mukachev MA
Jazyk: ruština
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1999 Nov-Dec (6), pp. 50-3.
Abstrakt: The word deals with the results obtained in the study of the reactogenicity and immunological activity of concentrated and inactivated tissue-culture tick-borne encephalitis vaccine, manufactured by the Chumakov Institute of Poliomyelitis and Viral Encephalitides, in the immunization of children and adolescents. The vaccine proved to be moderately reactogenic and exhibited pronounced immunological activity. In 91.5% of the immunized children the fourfold increase of the antibody level was observed. On the basis of the data obtained in this study the tick-borne encephalitis vaccine was recommended for use in medical practice for the prophylaxis of tick-borne encephalitis among children and adolescents.
Databáze: MEDLINE