| Autor: |
Tikhonov NG; Research Institute for Plague Control, Volgograd, Russia., Narbutovich NI, Khrapova NP, Prokhvatilova EV |
| Jazyk: |
ruština |
| Zdroj: |
Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1999 Nov-Dec (6), pp. 24-7. |
| Abstrakt: |
Phosphatase, phospholipase C and a proteolytic complex, including casein- and hemoglobin-hydrolases, have been isolated from cell-free extracts of B. pseudomallei cultivation medium. A set of monoclonal antibodies (McAb) to the antigenic complexes of this infective agent has been obtained. Conditions for the study of the interaction of the enzymes and McAb have been worked out, and most of the 14 immunoglobulins under study have been shown to neutralize 2-3 hydrolases each. Three types of McAb, selectively inhibiting only the proteolytic complex, only casein-hydrolase and only phospholipase C, have been identified. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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