| Autor: |
Buynak JD; Department of Chemistry, Southern Methodist University, Dallas, TX 75275-0314, USA. jbuynak@mail.smu.edu, Doppalapudi VR, Rao AS, Nidamarthy SD, Adam G |
| Jazyk: |
angličtina |
| Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2000 May 01; Vol. 10 (9), pp. 847-51. |
| DOI: |
10.1016/s0960-894x(00)00094-9 |
| Abstrakt: |
A series of 2-substituted-7-(alkylidene)cephalosporin sulfones were prepared and evaluated as beta-lactamase inhibitors. Compound 11c showed excellent activity as an inhibitor of the class C beta-lactamase derived from Enterobacter cloacae, strain P99. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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