Multicomponent linchpin couplings of silyl dithianes: synthesis of the Schreiber C(16-28) trisacetonide subtarget for mycoticins A and B.

Autor: Smith AB 3rd; Department of Chemistry, Monell Chemical Senses Center, University of Pennsylvania, Philadelphia 19104, USA. smithab@sas.upenn.edu, Pitram SM
Jazyk: angličtina
Zdroj: Organic letters [Org Lett] 1999 Dec 16; Vol. 1 (12), pp. 2001-4.
DOI: 10.1021/ol991166b
Abstrakt: [formula: see text] An efficient synthesis of trisacetonide (+)-11, the Schreiber C(16-28) subtarget for mycoticins A and B, is described. The key synthetic transformation entails a one-flask, five-component linchpin coupling tactic.
Databáze: MEDLINE