| Autor: |
Zani CL; Laboratório de Química de Produtos Naturais, Centro de Pesquisas René Rachou-FIOCRUZ, Belo Horizonte, MG, Brazil., Alves TM, Queiróz R, Fontes ES, Shin YG, Cordell GA |
| Jazyk: |
angličtina |
| Zdroj: |
Phytochemistry [Phytochemistry] 2000 Apr; Vol. 53 (8), pp. 877-80. |
| DOI: |
10.1016/s0031-9422(99)00564-6 |
| Abstrakt: |
An extract of the aerial parts from Alomia myriadenia Schultz-Bip. ex Baker (Asteraceae) showed significant cytotoxicity against a panel of human cancer cell lines in a screening of extracts from Brazilian Atlantic Forest plant species. Employing a bioassay-linked HPLC-electrospray/MS method, followed by semi-preparative HPLC, the active component was isolated and characterized as a mixture of epimers of the labdane diterpene 12S,16-dihydroxy-ent-labda-7,13-dien-15,16-olide. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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