Folate sufficient subjects do not accumulate additional folates during supplementation.

Autor: Santhosh-Kumar CR; Department of Medicine, Royal Hospital, Muscat, Oman., Bisping JS, Kick SD, Deutsch JC, Kolhouse JF
Jazyk: angličtina
Zdroj: American journal of hematology [Am J Hematol] 2000 May; Vol. 64 (1), pp. 71-2.
DOI: 10.1002/(sici)1096-8652(200005)64:1<71::aid-ajh13>3.0.co;2-z
Abstrakt: In a double-blinded placebo-controlled trial of folic acid supplementation in 82 alcoholic subjects, it was found that whole blood folate levels, determined by a mass spectrometric method, do not increase in subjects whose baseline folate levels are above the third quartile (folate sufficiency). Since a state of folate sufficiency can now be identified, a recommended daily allowance (RDA) for folate can be determined using objective means.
Databáze: MEDLINE