| Autor: |
Legros JY; Laboratoire de Catalyse Moleculaire associe au C.N.R.S., UPRESA 8075, Institut de Chimie Moleculaire d'Orsay, Universite de Paris-Sud, Orsay, France. jylegros@icmo.u-psud.fr, Primault G, Toffano M, Riviere MA, Fiaud JC |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2000 Feb 24; Vol. 2 (4), pp. 433-6. |
| DOI: |
10.1021/ol991274y |
| Abstrakt: |
[reaction: see text] Quinolylmethyl, 1-(isoquinolyl)ethyl, and 1-(quinolyl)ethyl acetates reacted with dimethylmalonate anion in the presence of a Pd(0) catalyst to give products of nucleophilic substitution and/or byproducts, depending upon the substitution pattern. The observed side reactions were reduction in the case of primary acetates and elimination or elimination/Michael-type addition sequence for secondary substrates. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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