| Autor: |
Spicher VM; Department of Pediatrics, University Hospital, Geneva, Switzerland., Berclaz PY, Cheseaux JJ, Morandi PA, Suter S, Wunderli W, Siegrist CA |
| Jazyk: |
angličtina |
| Zdroj: |
Clinical pediatrics [Clin Pediatr (Phila)] 2000 Apr; Vol. 39 (4), pp. 203-8. |
| DOI: |
10.1177/000992280003900402 |
| Abstrakt: |
A polymerase chain reaction kit (AMPLICOR EV) for the detection of enteroviruses (EV-PCR) in the cerebrospinal fluid (CSF) was evaluated in clinical conditions in a prospective blinded-intention study. Forty-three children (mean age 2.7 years) hospitalized for suspected meningitis or fever of unclear etiology were enrolled. EV-PCR was performed on a daily basis. Results were available in less than 2 days in 72% of cases. EV-PCR was positive in nine (21%) children, including three infants without CSF pleocytosis. Knowing their EV-PCR result would have allowed a saving of 18 hospital days and 12 days of antibiotic therapy. The EV-PCR in the CSF can thus be practically useful for children hospitalized for meningitis or fever if available on-site on a daily basis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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