| Autor: |
Jónasdóttir TJ; Norwegian School of Veterinary Science, Department of Morphology, Genetics and Aquatic Biology, Oslo, Norway. tora.jonasdottir@veths.no, Mellersh CS, Moe L, Vignaux F, Ostrander EA, Lingaas F |
| Jazyk: |
angličtina |
| Zdroj: |
Animal genetics [Anim Genet] 2000 Apr; Vol. 31 (2), pp. 123-6. |
| DOI: |
10.1046/j.1365-2052.2000.00601.x |
| Abstrakt: |
The canine tuberous sclerosis 2 (TSC2) gene has been mapped to canine chromosome 6 using a canine whole genome radiation hybrid panel. There is close linkage between canine TSC2 and the polycystic kidney disease 1 gene (PKD1), as has been observed in humans and other mammalian species. The gene responsible for the human juvenile form of neuronal ceroid lipofuscinosis (CLN3), maps close to TSC2 and PKD1 in humans, and is also syntenic in the dog. We further demonstrate linkage to a group of polymorphic markers assigned to canine chromosome 6 (CFA6). |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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