| Autor: |
Dellovade TL; Laboratory of Neurobiology and Behavior, The Rockefeller University, New York, New York 10021, USA., Chan J, Vennstrom B, Forrest D, Pfaff DW |
| Jazyk: |
angličtina |
| Zdroj: |
Nature neuroscience [Nat Neurosci] 2000 May; Vol. 3 (5), pp. 472-5. |
| DOI: |
10.1038/74846 |
| Abstrakt: |
The two genes coding for thyroid hormone receptors (TR) alpha 1 and beta have opposite effects on female sex behaviors. Deletion of TRalpha 1 reduced them, whereas deletion of TRbeta actually increased them. These results could not be attributed to altered levels of hormones in the blood, general alterations in estrogen responsiveness or altered general activity. Instead, they indicate a previously unknown molecular mechanism upon which the two TR genes exert opposite influences. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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