Sporadic acute hepatitis E in the united kingdom: an underdiagnosed phenomenon?

Autor: McCrudden R; Division of Cell and Molecular Medicine, D Level South Block Mail Point 811, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK. prm@soton.ac.uk, O'Connell S, Farrant T, Beaton S, Iredale JP, Fine D
Jazyk: angličtina
Zdroj: Gut [Gut] 2000 May; Vol. 46 (5), pp. 732-3.
DOI: 10.1136/gut.46.5.732
Abstrakt: Background: Hepatitis E (HEV) is the primary cause of enterically transmitted non-A non-B hepatitis worldwide. Case reports of HEV in individuals in the United Kingdom relate to travel to endemic areas or contact with individuals who have visited these areas.
Case Reports: Four individuals presented with acute hepatitis to a hepatology clinic in a teaching hospital. Serology confirmed acute hepatitis E in all four. Investigation by the Communicable Disease Control Department established no links between the cases, no travel to an endemic area, and no contacts.
Conclusion: Contrary to current belief, community acquired hepatitis E virus infection occurs sporadically in the United Kingdom and should be considered as a cause of seronegative hepatitis.
Databáze: MEDLINE