Sporadic acute hepatitis E in the united kingdom: an underdiagnosed phenomenon?
Autor: | McCrudden R; Division of Cell and Molecular Medicine, D Level South Block Mail Point 811, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK. prm@soton.ac.uk, O'Connell S, Farrant T, Beaton S, Iredale JP, Fine D |
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Jazyk: | angličtina |
Zdroj: | Gut [Gut] 2000 May; Vol. 46 (5), pp. 732-3. |
DOI: | 10.1136/gut.46.5.732 |
Abstrakt: | Background: Hepatitis E (HEV) is the primary cause of enterically transmitted non-A non-B hepatitis worldwide. Case reports of HEV in individuals in the United Kingdom relate to travel to endemic areas or contact with individuals who have visited these areas. Case Reports: Four individuals presented with acute hepatitis to a hepatology clinic in a teaching hospital. Serology confirmed acute hepatitis E in all four. Investigation by the Communicable Disease Control Department established no links between the cases, no travel to an endemic area, and no contacts. Conclusion: Contrary to current belief, community acquired hepatitis E virus infection occurs sporadically in the United Kingdom and should be considered as a cause of seronegative hepatitis. |
Databáze: | MEDLINE |
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