| Autor: |
Slătineanu SM; Disciplina de Fiziologie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi., Haulică I, Costuleanu A, Mândreci I, Petrescu G |
| Jazyk: |
Romanian; Moldavian; Moldovan |
| Zdroj: |
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi [Rev Med Chir Soc Med Nat Iasi] 1999 Jul-Dec; Vol. 103 (3-4), pp. 140-6. |
| Abstrakt: |
The effects of the conversion enzyme on the hydroelectrolytic balance in adult rats, maintained in standard lab conditions have been followed. The administration protocol for the conversion inhibitor (captopril) produced a blocking of the transformation of angiotensin I in angiotensin II only at the level of the cerebral structures, during the whole period of the treatment (40 micrograms/kg x 3/24 hours). Following the intracerebroventricular (ICV) administration of captopril, the fluid ingestion decreased diuresis and urinary elimination of Na+ and Ca++ increased. The results plead for the existence of a cerebral renin-angiotensin system, which intervenes in the control of the hydroelectrolyte metabolism. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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