Brain SPECT imaging in Huntington's disease before and after therapy with olanzapine. Case report.

Autor: Etchebehere EC; Department of Radiology, Faculdade de Ciências Médicas (FCM) da Universidade Estadual de Campinas (UNICAMP), Brazil. elba@mn-d.com, Lima MC, Passos W, Maciel Júnior JA, Santos AO, Ramos CD, Camargo EE
Jazyk: angličtina
Zdroj: Arquivos de neuro-psiquiatria [Arq Neuropsiquiatr] 1999 Sep; Vol. 57 (3B), pp. 863-6.
DOI: 10.1590/s0004-282x1999000500021
Abstrakt: Olanzapine, an atypical antipsychotic drug, was administered to a patient with Huntington's disease (HD) with marked choreiform movements. Brain SPECT with 99mTc-HMPAO was performed before and after treatment. Brain SPECT imaging has been performed in patients with HD in order to determine the status of basal ganglia perfusion. The use of brain SPECT with 99mTc-HMPAO before and after treatment in patients with HD has not been yet reported. The marked hypoperfusion of the basal ganglia on brain SPECT performed before therapy with olanzapine improved significantly after treatment.
Databáze: MEDLINE