Autor: |
Allen MP; CNS Discovery, Central Research Division, Pfizer Inc, Groton, CT 06340, USA., Blake JF, Bryce DK, Haggan ME, Liras S, McLean S, Segelstein BE |
Jazyk: |
angličtina |
Zdroj: |
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2000 Mar 20; Vol. 10 (6), pp. 523-6. |
DOI: |
10.1016/s0960-894x(00)00034-2 |
Abstrakt: |
3-Amino-3-phenylpropionamide derivatives were produced as small molecule mimics of the cyclic octapeptide octreotide from readily available imine 1. The compounds exhibit high affinity for the mu opioid receptor. |
Databáze: |
MEDLINE |
Externí odkaz: |
|